Spravato® Esketamine Therapy

Spravato® is the first prescription nasal spray used alongside an oral antidepressant to treat severe depression. It functions similarly to ketamine and is especially effective for:

✅ Adults with treatment-resistant depression
✅ Individuals who have not responded adequately to at least two different antidepressants during their current episode of major depressive disorder
✅ Adults experiencing depressive symptoms with suicidal thoughts or actions

Why Choose Spravato?

Unlike traditional antidepressants, which can take weeks to show results, Spravato Esketamine works rapidly—often within 24 hours—by directly targeting brain cells to relieve symptoms.

If you or a loved one is struggling with treatment-resistant depression, Spravato may offer the breakthrough relief you’ve been seeking. Contact us to learn more about eligibility and treatment options!

Frequently Asked Questions about Spravato

What is Spravato?

SPRAVATO® (esketamine) CIII nasal spray is a groundbreaking treatment that targets NMDA receptors in the brain to help reduce symptoms of severe depression. It is the first-of-its-kind FDA-approved medication for two critical subpopulations of major depressive disorder (MDD):

✅ Treatment-resistant depression (TRD) – For adults who have not responded to at least two different antidepressants.
✅ MDD with acute suicidal ideation or behavior – Providing rapid relief for individuals experiencing severe depressive symptoms.

Unlike traditional antidepressants, SPRAVATO® is not a pain reliever or anesthetic and must be used under medical supervision.

Is Spravato Safe?

We are REMS-certified (Risk Evaluation and Mitigation Strategy) to administer SPRAVATO® safely and effectively. Our trained medical staff follows strict protocols to ensure patient safety:

  • Direct supervision during self-administration of the nasal spray.

  • Two-hour monitoring period after each dose to observe for potential side effects.

  • Transportation required – Patients cannot drive or operate machinery until the next day after a full night’s rest.

How quickly does Spravato work?

Unlike traditional antidepressants that take weeks to work, Spravato® can provide symptom relief within 24 hours. If you have tried two or more antidepressants without success, talk to our psychiatrist about whether Spravato® is right for you.

Potential Side Effects

Common side effects may occur immediately after taking Spravato® and typically resolve the same day. These include:

  • Dissociation

  • Dizziness

  • Fatigue

  • Nausea/Vomiting

  • Feeling drunk or euphoric

  • Anxiety or numbness

  • Spinning sensation

Who Should NOT Take Spravato®?

Spravato® is not recommended for individuals with:

🚫 Aneurysms or blood vessel disease
🚫 Abnormal blood vessel connections (arteriovenous malformation)
🚫 History of brain bleeding
🚫 Allergic reaction to esketamine or ketamine

If you or a loved one is struggling with treatment-resistant depression, Spravato® may provide the breakthrough relief you need. Contact us to learn more about eligibility and treatment options!